Creative Biolabs Updates Its Antibody Library Screening Service

May 15 16:22 2019

New York, US–May 15, 2019 Creative Biolabs, a company located in New York, recently updated its antibody library screening service. To date, this leader in antibody manufacturing and engineering has become capable of screening a wide range of antibody libraries by adopting various phage display library screening strategies. Moreover, the newest service has broad applications in antibody based research, such as in antibody discovery, affinity maturation and humanization, etc.


Nowadays, phage display techniques are widely used for the study of protein-protein, protein-peptide and protein-DNA interactions, particularly for the discovery of specific antibodies, scaffolds or ligands. In the constructed libraries, binders with desired specificity generally exist at low frequencies. Thus, phage display antibody library screening is frequently used to enrich and identify the binders with high affinity and specificity from libraries of interest.


“As a top phage display company, Creative Biolabs has been committed to offering its worldwide clients the best phage display library screening services. Now, we become able to take distinct strategies to serve our customers, such as solid-phase, solution-sorting, cell-based, in vivo and ex vivo screening. These strategies can be used for discovery of therapeutic antibodies and pH-sensitive biomolecules, and for screening of premade antibody libraries, premade single domain antibody libraries, premade peptide library, protease substrate, internalization antibodies and thermal stable scFv/Fab,” said a scientist from Creative Biolabs.


Antibody libraries are constructed by genes encoding antibody variable domains derived from the B cells of immune or naïve donors. In comparison to the traditional hybridoma method, the antibody phage display library has striking advantages in discovering new monoclonal antibodies and even the full human antibodies. For instance, the scFv libraries are genetically stable due to its small size, whereas the Fab libraries can help streamline the selection and characterization procedure.


The same scientist from Creative Biolabs added that “Through years of efforts in antibody library screening, our company has become able to establish immune antibody libraries and isolate monoclonal antibodies with high specificity and affinity from a variety of species, including monkeys, llama, camels, sharks, alligators and ferrets. On top of antibody discovery, affinity maturation and humanization, the application of our screening service has extended to the identification of enzyme inhibitors, epitope mapping on antigens, and the discovery of new therapeutic targets and interactions between ligands and receptors.”


Undoubtedly, the improvement of the antibody library screening service marks a giant step forward for the pharmaceutical industry, especially for the antibody based research. This new service not only significantly satisfies the diverse market demands for screening of different types of antibody libraries, but enlarges the opportunity of screening techniques to be used in wider areas. With the improvement of phage display techniques, more screening strategies will be put forward to better screen antibody libraries.


About Creative Biolabs


Creative Biolabs is a leading custom service provider, boasting rich experience in antibody production and engineering. Its service portfolio includes mouse and rat monoclonal antibody production using hybridoma technology, human, monkey, rabbit, chicken, dog, llama and camel monoclonal antibody production using various antibody library technologies. In addition, the company also conducts in-depth antibody humanization and affinity maturation.

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Company Name: Creative Biolabs
Contact Person: Candy Swift
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Phone: 1-631-619-7922
Address:45-1 Ramsey Road
City: Shirley
State: New York
Country: United States